Volume 1: 2012 – 2016
2012
J Chromatogr A. 2012 Sep 21; 1256:232-9. doi: 10.1016/j.chroma.2012.07.064. Epub 2012 Jul 28.
Comparison of multiple linear regression, partial least squares and artificial neural networks for prediction of gas chromatographic relative retention times of trimethylsilylated anabolic androgenic steroids.Fragkaki AG, Farmaki E, Thomaidis N, Tsantili-Kakoulidou A, Angelis YS, Koupparis M, Georgakopoulos C.
Bioanalysis. 2012 Jul;4(13):1667-80. doi: 10.4155/bio.12.146.
Evolving concepts and techniques for anti-doping.Friedmann T, Flenker U, Georgakopoulos C, Alsayrafi M, Sottas PE, Williams SA, Gill RD.
Bioanalysis. 2012 Jul;4(13):1549-63. doi: 10.4155/bio.12.148.
Analytical progresses of the International Olympic Committee and World Anti-Doping Agency Olympic laboratories.Georgakopoulos C, Saugy M, Giraud S, Robinson N, Alsayrafi M.
Bioanalysis. 2012 Jan;4(2):167-75. doi: 10.4155/bio.11.308.
Two-step derivatization procedures for the ionization enhancement of anabolic steroids in LC-ESI-MS for doping control analysis.Athanasiadou I, Angelis YS, Lyris E, Vonaparti A, Thomaidis NS, Koupparis MA,Georgakopoulos C.
Int J Lab Hematol. 2012 Dec;34(6):641-7. doi: 10.1111/j.1751-553X.2012.01450.x. Epub 2012 Jul 16.
The impact of long-haul air travel on variables of the athlete's biological passport.Schumacher YO, Klodt F, Nonis D, Pottgiesser T, Alsayrafi M, Bourdon PC, Voss SC.Y. O.
Exp Clin Endocrinol Diabetes. 2013 Aug;121(8):475-82. doi: 10.1055/s-0033-1343395. Epub 2013 Sep 11.
Endurance exercise alters cellular immune status and resistin concentrations in men suffering from non-insulin-dependent type 2 diabetes.Wenning P, Kreutz T, Schmidt A, Opitz D, Graf C, Voss S, Bloch W, Brixius K.
2013
Analytical Chemistry Volume 42, January 2013, Pages 137-156
Chemical derivatization to enhance ionization of anabolic steroids in LC-MS for doping-control analysis.Ioanna Athanasiadou, Yiannis S. Angelis, Emmanouil Lyris and Costas Georgakopoulos
Br J Sports Med. 2013 Dec;47 Suppl 1:i59-69. doi: 10.1136/bjsports-2013-092559.
Adding heat to the live-high train-low altitude model: a practical insight from professional football.Buchheit M, Racinais S, Bilsborough J, Hocking J, Mendez-Villanueva A, Bourdon PC, Voss S, Livingston S, Christian R, Périard J, Cordy J, Coutts AJ.
Clin Chim Acta. 2013 Oct 21;425:242-58. doi: 10.1016/j.cca.2013.07.031. Epub 2013 Aug 14.
Sports doping: emerging designer and therapeutic β2-agonists.Fragkaki AG1, Georgakopoulos C, Sterk S, Nielen MW.
Free Radic Res. 2013 Aug;47 Suppl 1:39-48. doi: 10.3109/10715762.2013.789136. Epub 2013 Apr 25.
Reactive aldehydes--second messengers of free radicals in diabetes mellitus.Jaganjac M, Tirosh O, Cohen G, Sasson S, Zarkovic N.
J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 15;941:69-80. doi: 10.1016/j.jchromb.2013.10.008. Epub 2013 Oct 16.
A generic screening methodology for horse doping control by LC-TOF-MS, GC-HRMS and GC-MS.Kioussi MK, Lyris EM, Angelis YS, Tsivou M, Koupparis MA, Georgakopoulos CG.
Prostaglandins Other Lipid Mediat. 2013 Oct;106:1-7. doi:10.1016/j.prostaglandins.2013.07.003. Epub 2013 Jul 18.
Differential actions of the prostacyclin analogues treprostinil and iloprost and the selexipag metabolite, MRE-269 (ACT-333679) in rat small pulmonary arteries and veins.Orie NN, Ledwozyw A, Williams DJ, Whittle BJ, Clapp LH.
Molecules. 2013 Oct 10;18(10):12441-63. doi: 10.3390/molecules181012441.
Protein adsorption on various plasma-treated polyethylene terephthalate substrates.Recek N, Jaganjac M, Kolar M, Milkovic L, Mozetič M, Stana-Kleinschek K, Vesel A.
Int J Sports Med. 2014 Feb;35(2):89-94. doi: 10.1055/s-0033-1345177. Epub 2013 Jul 18.
Variability of serum markers of erythropoiesis during 6 days of racing in highly trained cyclists.Voss SC, Alsayrafi M, Bourdon PC, Klodt F, Nonis D, Hopkins WG, Schumacher YO.
Growth Horm IGF Res. 2013 Aug;23(4):105-8. doi: 10.1016/j.ghir.2013.03.006. Epub 2013 Apr 19.
The effect of a period of intensive exercise on the isoform test to detect growth hormone doping in sports.Voss SC, Giraud S, Alsayrafi M, Bourdon PC, Schumacher YO, Saugy M, Robinson N.
J Proteomics. 2013 Oct 30;92:239-47. doi: 10.1016/j.jprot.2013.02.004. Epub 2013 Feb 22.
Pathophysiological relevance of aldehydic protein modifications.Zarkovic N, Cipak A, Jaganjac M, Borovic S, Zarkovic K.
2014
Bioanalysis. 2014 Mar;6(6):881-96. doi: 10.4155/bio.14.9. Review.
Advances in the detection of designer steroids in anti-doping.Abushareeda W, Fragkaki A, Vonaparti A, Angelis Y, Tsivou M, Saad K, Kraiem S, Lyris E, Alsayrafi M, Georgakopoulos C.
J Pharm Biomed Anal. 2014 Mar;90:207-14. doi: 10.1016/j.jpba.2013.12.004. Epub 2013 Dec 14.
Gas chromatographic–mass spectrometric quantitation of busulfan inhuman plasma for therapeutic drug monitoring: A new on-linederivatization procedure for the conversion of busulfan to1,4-diiodobutane.Ioanna Athanasiadou, Yiannis S. Angelis, Emmanouil Lyris, Helen Archontaki, Costas Georgakopoulos, Georgia Valsami
J Mass Spectrom. 2015 May;50(5):740-8. doi: 10.1002/jms.3583.
Comparison of sulfo-conjugated and glucoconjugated urinary metabolites for detection of methenolone misuse in doping control by LC-HRMS, GC-MS and GC-HRMS.G. Fragkaki, Y. S. Angelis, P. Kiousi, C. Georgakopoulos and E. Lyris
ACS Chem Biol. 2014 Mar 21;9(3):802-11. doi: 10.1021/cb400728e. Epub 2014 Jan 17.
Discovery of Highly Potent p53-MDM2 Antagonists and Structural Basis for Anti-Acute Myeloid Leukemia Activities.Yijun Huang, Siglinde Wolf, Barbara Beck, Lisa-Maria Köhler, Kareem Khoury, Grzegorz M. Popowicz, Sayed K Goda, Marion Subklewe, Aleksandra Twarda, Tad A. Holak, and Alexander Dömling
J Anal Toxicol. 2014 Jan-Feb;38(1):16-23. doi: 10.1093/jat/bkt089. Epub 2013 Nov 4.
A Synopsis of the Adverse Analytical and Atypical Findings Between 2005 and 2011 from the Doping Control Laboratory of Athens in Greece.Nassia Kioukia-Fougia, Argyro Fragkaki, Polyxeni Kiousi, Irene-Pelagia Leontiou, Helen Dimopoulou, Maria Tsivou, Emmanouil Lyris and Costas Georgakopoulos
Molecules. 2013 Oct 10;18(10):12441-63. doi: 10.3390/molecules181012441.
Adsorption of Proteins and Cell Adhesion to Plasma Treated Polymer Substrates.Nina Recek, Miran Mozetic, Morana Jaganjac, Lidija Milkovic, Neven Zarkovic, and Alenka Vesel
Growth Horm IGF Res. 2013 Aug;23(4):105-8. doi: 10.1016/j.ghir.2013.03.006. Epub 2013 Apr 19.
The effect of a period of intensive exercise on the isoform test to detect growth hormone doping in sports.S.C. Voss, S. Giraud, M. Alsayrafi, P.C. Bourdon, Y.O. Schumacher, M. Saugy and N. Robinson
2015
Drug Test Anal. 2015 Nov-Dec;7(11-12):1017-24. doi: 10.1002/dta.1917.
The effect of fasting during Ramadan on parameters of the haematological and steroidal modules of the athletes biological passport – a pilot study.K. Alsaadi, S.C. Voss, S. Kraiem, A. Alwahaibi, S. Alyazedi, N. Dbes, R. Goebel, V. Mohamed-Ali, S. Alsowaidi, A.M. Seyam, A.S. Bashraheel, M. Alsayrafia and C. Georgakopoulos
Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):46-52. doi: 10.1016/j.prostaglandins.2015.09.002. Epub 2015 Sep 8.
Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.Chabha Benyahia, Gulsev Ozen, Nelson Orie, Agatha Ledwozyw, Liliane Louedec, Fangfang Li, Amira M. Senbel, Adam Silverstein, Claire Danel, Dan Longrois, Lucie H. Clapp, Xavier Norel, Gökc¸ Topal
Biol Sport. 2016 Mar;33(1):23-8. doi: 10.5604/20831862.1180173. Epub 2015 Nov 19.
The effect of cumulative endurance exercise on leptin and adiponectin and their role as markers to monitor training load.Voss SC, Nikolovski Z, Bourdon PC, Alsayrafi M, Schumacher YO
J Mass Spectrom. 2015 Dec;50(12):1409-19. doi: 10.1002/jms.3715.
Markers of mesterolone abuse in sulfate fraction for doping control in human urine.P. Kiousi, Y. S. Angelis, A. G. Fragkaki, W. Abushareeda, M. Alsayrafi,C. Georgakopoulos and E. Lyris
Journal of Nanoparticle Research, June 2015, 17:253
Permeation of platinum and rhodium nanoparticles through intact and damaged human skin.Marcella Mauro, Matteo Crosera, Carlotta Bianc. Gianpiero Adami, Tiziano Montini, Paolo Fornasiero. Morana Jaganjac. Massimo Bovenzi, Francesca Larese Filon
2016
Diabetologia. 2016 Nov;59(11):2406-2416. doi: 10.1007/s00125-016-4031-3. Epub 2016 Jun 24.
Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance.Shamma Almuraikhy, Wael Kafienah, Moataz Bashah, Ilhame Diboun, Morana Jaganjac, Fatima Al-Khelaifi, Houari Abdesselem, Nayef A. Mazloum, Mohammed Alsayrafi, Vidya Mohamed-Ali, Mohamed A. Elrayess
Bioanalysis. 2016 Nov;8(21):2265-2279. Epub 2016 Sep 26.
Analytical progresses of the World Anti- Doping Agency Olympic laboratories: a 2016 update from London to Rio.Ioanna Athanasiadou, Sven Voss, Emmanouil Lyris, Amina Aljaber, Mohammed Alsayrafi1 & Costas Georgakopoulos
Drug Test Anal. 2017 Jul;9(7):1062-1072. doi: 10.1002/dta.2104. Epub 2016 Nov 4.
Quantification of three beta-lactam antibiotics in breast milk and human plasma by hydrophilic interaction liquid chromatography/positive-ion electrospray ionization mass spectrometry.Evaggelos Kiriazopoulos, Sabina Zaharaki, Ariadni Vonaparti, Panagiota Vourna, Eirini Panteri-Petratou, Dimitra Gennimata, Kara Lombardo and Irene Panderi
Volume 2: 2017 – 2019
2017
Drug Test Anal. 2017 May;9(5):699-712. doi: 10.1002/dta.2048. Epub 2016 Sep 21.
Doping control container for urine stabilization: a pilot study.Maria Tsivou, Evangelia Giannadaki, Fiona Hooghe, Kris Roels, Wim Van Gansbeke, Flaminia Garribba, Emmanouil Lyris, Koen Deventer, Monica Mazzarino, Francesco Donati, Dimitrios G. Georgakopoulos, Peter Van Eenoo, Costas G. Georgakopoulos, Xavier de la Torred, Francesco Botrè
Free Radic Biol Med. 2017 Mar;104:129-137. doi: 10.1016/j.freeradbiomed.2017.01.015. Epub 2017 Jan 12.
4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance.Mohamed A. Elrayess, Shamma Almuraikhy, Wael Kafienah, Afnan Al-Menhali, Fatima Al-Khelaifi, Moataz Bashah, Kamelija Zarkovic, Neven Zarkovic, Georg Waeg, Mohammed Alsayrafi, Morana Jaganjac
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:74-83. doi: 10.1016/j.jchromb.2017.08.019. Epub 2017 Aug 19.
Gas chromatographic quadrupole time-of-flight full scan high resolution mass spectrometric screening of human urine in antidoping analysis.Wadha Abushareeda, Emmanouil Lyris, Suhail Kraiem, Aisha Al Wahaibi, Sameera Alyazidi, Najib Dbes, Arjen Lommenc Michel Nielen, Peter L. Horvatovich, Mohammed Alsayrafi, Costas Georgakopoulos
May 2017 Journal of Applied Pharmaceutical Science 7(5):39-45, DOI: 10.7324/JAPS.2017.70507
Cistanche tubulosa induces reactive oxygen species-mediated apoptosis of primary and metastatic human colon cancer cells.Afnan Saleh Al-Menhali, Safya Ali Jameela, Aishah A. Latiff, Mohamed A. Elrayess, Mohammed Alsayrafi, Morana Jaganjac
Redox Biol. 2017 Aug;12:483-490. doi: 10.1016/j.redox.2017.03.012. Epub 2017 Mar 16.
Combined metformin and insulin treatment reverses metabolically impaired omental adipogenesis and accumulation of 4-hydroxynonenal in obese diabetic patients.Morana Jaganjac, Shamma Almuraikhy, Fatima Al-Khelaifi, Mashael Al-Jaber, Moataz Bashah, Nayef A. Mazloum, Kamelija Zarkovic, Neven Zarkovic, Georg Waegg, Wael Kafienah, Mohamed A. Elrayess
Drug Test Anal. 2017 Nov;9(11-12):1794-1798. doi: 10.1002/dta.2212. Epub 2017 Jun 20.
Analysis of RBC‐microparticles in stored whole blood bags – a promising marker to detect blood doping in sports?Sven Christian Voss, Morana Jaganjac, Amna Mohamed Al‐Thani, Jean‐Charles Grivel, Christophe Michel Raynaud, Hind Al‐Jaber, Afnan Saleh Al‐Menhali, Zeyed Ahmad Merenkov, Mohammed Alsayrafi, Aishah Latiffa, Costas Georgakopoulos
Redox Biol. 2017 Apr;11:600-605. doi: 10.1016/j.redox.2017.01.005. Epub 2017 Jan 11.
Positron emission tomography-computed tomography and 4-hydroxynonenal-histidine immunohistochemistry reveal differential onset of lipid peroxidation in primary lung cancer and in pulmonary metastasis of remote malignancies.Nevenka Piska Živković, Mladen Petrovečki, Čedna Tomasović Lončarić, Igor Nikolića, Georg Waeg, Morana Jaganjac, Kamelija Žarković, Neven Žarković
2018
Rapid Commun Mass Spectrom. 2018 Dec 15;32(23):2055-2064. doi: 10.1002/rcm.8281.
Comparison of gas chromatography/quadrupole time‐of‐flight and quadrupole Orbitrap mass spectrometry in anti‐doping analysis: I. Detection of anabolic‐androgenic steroids.Wadha Abushareeda, Marc Tienstra, Arjen Lommen, Marco Blokland, Saskia Sterk, Suhail Kraiem, Peter Horvatovich, Michel Nielen, Muhammad Al‐Maadheed, Costas Georgakopoulos
Rapid Commun Mass Spectrom. 2018 Dec 15;32(23):2055-2064. doi: 10.1002/rcm.8281.
High resolution full scan liquid chromatography mass spectrometrycomprehensive screening in sports antidoping urine analysis.Wadha Abushareeda, Ariadni Vonaparti, Khadija Al Saad, Moneera Almansoori,Mbarka Meloug, Amal Saleh, Rodrigo Aguilera, Yiannis Angelis, Peter L. Horvatovich, Arjen Lommen, Mohammed Alsayrafi, Costas Georgakopoulos
J Transl Med. 2018 Jun 26;16(1):175. doi: 10.1186/s12967-018-1548-x.
Triglyceride profiling in adipose tissues from obese insulin sensitive, insulin resistant and type 2 diabetes mellitus individuals.Haya Al‑Sulaiti, Ilhame Diboun, Sameem Banu, Mohamed Al‑Emadi, Parvaneh Amani, Thomas M. Harvey, Alex S. Dömling, Aishah Latiff, Mohamed A. Elrayess
J Int Soc Sports Nutr. 2018 Sep 27;15(1):48. doi: 10.1186/s12970-018-0254-7.
Metabolomics profiling of xenobiotics in elite athletes: relevance to supplement consumption.Fatima Al-Khelaifi, Ilhame Diboun, Francesco Donati, Francesco Botrè, Mohammed Alsayrafi, Costas Georgakopoulos, Noha A. Yousri, Karsten Suhre, Mohamed A. Elrayess
Sports Med Open. 2018 Jan 5;4(1):2. doi: 10.1186/s40798-017-0114-z.
A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines.Fatima Al-Khelaifi, Ilhame Diboun, Francesco Donati, Francesco Botrè, Mohammed Alsayrafi
Oxid Med Cell Longev. 2018 Nov 8;2018:6375379. doi: 10.1155/2018/6375379. eCollection 2018.
Whole Blood Storage in CPDA1 Blood Bags Alters Erythrocyte Membrane Proteome.Amna Mohamed Al-Thani, Sven Christian Voss, Afnan Saleh Al-Menhali, Andrei Barcaru, Peter Horvatovich, Hind Al Jaber, Zoran Nikolovski, Aishah Latiff, Costas Georgakopoulos, Zeyd Merenkov, Jordi Segura, Mohammed Alsayrafi, Morana Jaganjac
Molecules. 2018 Jun 27;23(7). pii: E1548. doi: 10.3390/molecules23071548.
Hydrophilic Interaction Liquid Chromatography-Electrospray Ionization Mass Spectrometry for Therapeutic Drug monitoring of Metformin and Rosuvastatin in Human Plasma.Nikolaos Antonopoulos, Giorgos Machairas, George Migias, Ariadni Vonaparti, Vasiliki Brakoulia, Constantinos Pistos, Dimitra Gennimata, Irene Panderi
Drug Test Anal. 2018 Sep;10(9):1458-1468. doi: 10.1002/dta.2403. Epub 2018 May 30.
The effect of athletes` hyperhydration on the urinary ‘steroid profile’ markers in doping control analysis.I. Athanasiadou, S. Kraiem, S. Al‐Sowaidi, H. Al‐Mohammed, N. Dbes, S. Al‐Yazedi, W. Samsam, V. Mohamed‐Ali, A. Dokoumetzidis, M. Alsayrafi, G. Valsami, C. Georgakopoulos
Chemosphere. 2018 Oct;209:268-276. doi: 10.1016/j.chemosphere.2018.06.108. Epub 2018 Jun 18
Association of polybrominated diphenyl ethers in two fat compartments with increased risk of insulin resistance in obese individuals.Murad Helaleh, Ilhame Diboun, Nada Al-Tamimi, Haya Al-Sulaiti, Mohamed Al-Emadi, Aishah Madani, Nayef A Mazloum, Aishah Latiff, Mohamed A. Elrayess
Nat Commun. 2018 Jun 12;9(1):2293. doi: 10.1038/s41467-018-04422-2.
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease.Marthe H.R. Ludtmann, Plamena R. Angelova, Mathew H. Horrocks, Minee L. Choi, Margarida Rodrigues, Artyom Y. Baev, Alexey V. Berezhnov, Zhi Yao, Daniel Little, Blerida Banushi, Afnan Saleh Al-Menhali, Rohan T. Ranasinghe, Daniel R. Whiten, Ratsuda Yapom, Karamjit Singh Dolt, Michael J. Devine, Paul Gissen, Tilo Kunath, Morana Jaganjac, Evgeny V. Pavlov, David Klenerman, Andrey Y. Abramov , Sonia Gandhi
Talanta. 2018 Jun 1;183:131-141. doi: 10.1016/j.talanta.2018.02.068. Epub 2018 Feb 17.
Development and validation of a hydrophilic interaction liquid chromatography method for the quantitation of impurities in fixed-dose combination tablets containing rosuvastatin and metformin.George Machairas, Irene Panderi, Ariadni Geballa-Koukoula, Stavroula Rozou, Nikolaos Antonopoulos, Christos Charitos, Ariadni Vonaparti
PLoS One. 2018 Apr 26;13(4):e0196254. doi: 10.1371/journal.pone.0196254. eCollection 2018.
Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.Fatma B. Rashidi, Alanod D. AlQhatani, Sara S. Bashraheel, Shabnam Shaabani, Matthew R. Groves, Alexander DoÈ mling, Sayed K. Goda
Sci Total Environ. 2018 Oct 1;637-638:41-49. doi: 10.1016/j.scitotenv.2018.04.433. Epub 2018 May 9.
S-metolachlor promotes oxidative stress in greenmicroalga Parachlorella kessleri - A potential environmental and health risk for higher organisms.Dubravka Špoljarić Maronić, Ivna Štolfa Čamagajevac, Janja Horvatić, Tanja Žuna Pfeiffer, Filip Stević , Neven Žarković, Georg Waeg, Morana Jaganjac
2019
Scand J Med Sci Sports. 2019 Jul;29(7):933-943. doi: 10.1111/sms.13425. Epub 2019 Apr 29.
Metabolic profiling of elite athletes with different cardiovascular demand.Fatima Al‐Khelaifi, Francesco Donati, Francesco Botre, Aishah Latiff, David Abraham, Aroon Hingorani, Costas Georgakopoulos, Karsten Suhre, Noha A. Yousri, Mohamed A. Elrayess
Journal of Advances in Medicine and Medical Research, 2019 - Volume 30 [Issue 9], 1-10, Oct 4, 2019
Administration of Combined Methanolic Leaf Extracts of Vernonia amygdalina and Gongronema latifolium Enhanced Glut 2 Expression in the Pancreas and Downregulates Serum Caspase 3 Activity of Streptozotocin-Induced Diabetic Wistar Rats.M. I. Akpaso, N. N. Orie, P. E. Ebong
Journal of Herbs, Spices & Medicinal Plants, Volume 25, 2019 - Issue 3
Evaluation of Apoptotic, Antiproliferative, and Antimigratory Activity of Origanum syriacum against Metastatic Colon Cancer Cells.Sara S. Aldisi, Morana Jaganjac, Ali H. Eid, Ipek Goktepe
Toxicol Rep. 2019 Sep 24;6:975-982. doi: 10.1016/j.toxrep.2019.09.009. eCollection 2019.
Dietary exposure of the Qatari population to food mycotoxins and reflections on the regulation limits.Muna Al Jabira, Andrei Barcarub, Aishah Latiff, Morana Jaganjac, Gouda Ramadan, Peter Horvatovich
Food Chem Toxicol. 2019 Jul;129:211-228. doi: 10.1016/j.fct.2019.04.047. Epub 2019 Apr 26.
Aflatoxin, fumonisin, ochratoxin, zearalenone and deoxynivalenol biomarkers in human biological fluids: A systematic literature review, 2001–2018Belqes Ahmad Al-Jaal, Morana Jaganjac, Andrei Barcaru, Peter Horvatovich, Aishah Latiff
Toxicon. 2019 Oct 3;171:43-50. doi: 10.1016/j.toxicon.2019.10.003
Mycotoxin contamination of food and feed in the Gulf Cooperation Council countries and its detection.Belqes Al-Jaal, Sofia Salama, Noof Al-Qasmi, Morana Jaganjac
Eur J Pharm Sci. 2019 Jan 15;127:79-91. doi: 10.1016/j.ejps.2018.10.014. Epub 2018 Oct 19
Production of “biobetter” glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment.Alanod D. AlQahtania,b,1, Layla Al-mansooria,c,1, Sara S. Bashraheela,b, Fatma B. Rashidid,⁎, Afrah Al-Yafeia, Philip Elsingac, Alexander Domlingb, Sayed K. Goda
Biomed Pharmacother. 2019 Apr;112:108725. doi: 10.1016/j.biopha.2019.108725. Epub 2019 Feb 28.
Production of “biobetter” variants of glucarpidase with enhanced enzyme activity.Alanod D. Al-Qahtania,b,1, Sara S. Bashraheela,b,1, Fatma B. Rashidic, C. David O’Connord, Atilio Reyes Romero, Alexander Domling, Sayed K. Goda
Biomed Pharmacother. 2019 May;113:108750. doi: 10.1016/j.biopha.2019.108750. Epub 2019 Mar 5.
Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatmentAlanod D. AlQahtani, David O’Connor, Alexander Domling, Sayed K. Goda
Scand J Med Sci Sports. 2019 Oct;29(10):1489-1500. doi: 10.1111/sms.13499. Epub 2019 Jul 5.
Effect of hyperhydration on the pharmacokinetics and detection of orally administered budesonide in doping control analysis.Ioanna Athanasiadou, Ariadni Vonaparti, Aristeidis Dokoumetzidis, Amal Saleh, Miriam Mbeloug, Mohammed Al‐Maadheed, Georgia Valsami, Costas Georgakopoulos
J Pharm Sci. 2019 Jun;108(6):2162-2172. doi: 10.1016/j.xphs.2019.01.017. Epub 2019 Jan 23.
Hyperhydration Effect on Pharmacokinetic Parameters and Detection Sensitivity of Recombinant Human Erythropoietin in Urine and Serum Doping Control Analysis of Males.Ioanna Athanasiadou, Aristeidis Dokoumetzidis, Sven Christian Voss, Wesal El Saftawy, Mohammed Al-Maadheed, Georgia Valsami, Costas Georgakopoulos
Int J Sport Nutr Exerc Metab. 2019 Jul 1;29(4):388–396. doi: 10.1123/ijsnem.2018-0213.
Hyperhydration-Induced Decrease in Urinary Luteinizing Hormone Concentrations of Male Athletes in Doping Control Analysis.Ioanna Athanasiadou, Sven Christian Voss, Wesal El Saftawy, Hind Al-Jaber, Najib Dbes, Sameera Al-Yazedi, Waseem Samsam, Vidya Mohamed-Ali, Mohammed Alsayrafi, Georgia Valsami, Costas Georgakopoulos
Biomed Pharmacother. 2019 Jul;115:108905. doi: 10.1016/j.biopha.2019.108905.
Studies on vascular response to full superantigens and superantigen derived peptides: Possible production of novel superantigen variants with less vasodilation effect for tolerable cancer immunotherapy.Sara S. Bashraheel, Alanod D. AlQahtani, Fatma B. Rashidi, Haya Al-Sulaiti, Alexander Domling, Nelson N. Orie, Sayed K. Goda
Cells. 2019 Mar 29;8(4). pii: E292. doi: 10.3390/cells8040292.
The Role of Acrolein and NADPH Oxidase in the Granulocyte-Mediated Growth-Inhibition of Tumor Cells.Morana Jaganjac, Tanja Matijevic Glavan, Neven Zarkovic
Chromatography on line.
Automated Gas and Liquid Chromatography Retention Time Modelling and Prediction Using Open-Access Molecular Database Structures and Quantitative Structure-Chromatography Retention Relationships.Arjen Lommen, Khetam Al-Saadi, Peter L. Horvatovich, Ariadni Vonaparti, Mohammed Al Maadheed, Michel W.F. Nielen, Costas Georgakopoulos
Rapid Commun Mass Spectrom. 2019 Oct 30;33(20):1578-1588. doi: 10.1002/rcm.8507.
Ultra‐fast retroactive processing of liquid chromatography high‐resolution full‐scan Orbitrap mass spectrometry data in anti‐doping screening of human urine.Arjen Lommen, Abdurzag Elaradi, Ariadni Vonaparti, Marco Blokland, Michel W. Nielen, Khadija Ali Saad, Wadha Masoud Abushreeda, Peter Horvatovich, Amal Essa Al‐Muraikhi, Mohammed Al‐Maadheed, Costas Georgakopoulos
Steroids. 2019 Aug 22;152:108477. doi: 10.1016/j.steroids.2019.108477.
Population reference ranges of urinary endogenous sulfate steroids concentrations and ratios as complement to the steroid profile in sports antidoping.Khadija Saada, Ariadni Vonapartia, Ioanna Athanasiadoua, Amal Saleha, Wadha Abushareedaa, Aisha Alwahaibia, Bibi Fatima Ajab Khana, Rodrigo Aguileraa, Souheil Kraiema, Peter L. Horvatovichb, Amal Essa Al-Muraikhia, Mohammed Al Maadheeda, Costas Georgakopoulos
Volume 3: 2020 – 2022
2020
Drug Test Anal. 2020 Nov;12(11-12):1544-1553. doi: 10.1002/dta.2887
Alternative markers for Methylnortestosterone misuse in human urine.Sakellariou, P., Kiousi, P., Fragkaki, A. G., Lyris, E., Petrou, M., Georgakopoulos, C., & Angelis, Y. S.
Front Mol Biosci. 2021 Oct 26;8:728273. doi: 10.3389/fmolb.2021.728273.
Benefit from the Multi-Omics Approach Over Single Biomarker Assessment and Implications for Testing, Long-term Storage and Re-testing of Anti-Doping Samples.Lima, G., Kolliari-Turner, A., Malinsky, F., Guppy, F., Martin, R. P., Wang, G., Voss, S.C., Georgakopoulos, C., Borrione, P., Pigozzi, F., & Pitsiladis, Y.
J Sports Sci. 2020 Aug;38(16):1924-1932. doi: 10.1080/02640414.2020.1763772.
Benefit from the Hyperhydration using different hydration agents does not affect the haematological markers of the athlete biological passport in euhydrated volunteers.Athanasiadou, I., Christian Voss, S., El Saftawy, W., Al-Maadheed, M., Valsami, G., & Georgakopoulos, C.
Frontiers in Genetics. 2020 Jun 16;11:595. doi: 10.3389/fgene.2020.00595
Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism.Al-Khelaifi, F., Yousri, N. A., Diboun, I., Semenova, E. A., Kostryukova, E. S., Kulemin, N. A., Borisov, O. V., Andryushchenko, L. B., Larin, A. K., Generozov, E. V., Miyamoto-Mikami, E., Murakami, H., Zempo, H., Miyachi, M., Takaragawa, M., Kumagai, H., Naito, H., Fuku, N., Abraham, D., Hingorani, A. Elrayess, M. A.
Sci Rep. 2020 Jun 23;10(1):10473.doi: 10.1038/s41598-020-67555-9
Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance. Scientific reports, 10(1), 10473.Al-Khelaifi, F., Diboun, I., Donati, F., Botrè, F., Abraham, D., Hingorani, A., Albagha, O., Georgakopoulos, C., Suhre, K., Yousri, N. A., & Elrayess, M. A.
Bioanalysis. 2020 Jun;12(11):719-722. doi: 10.4155/bio-2020-0137
Metabolomics and doping analysis: promises and pitfalls.Botrè, F., Georgakopoulos, C., & Elrayess, M. A.
Drug Test Anal. 2020 May;12(5): 641-646.doi: 10.1002/dta.2721
Detecting - the 2004 Athens Olympic GamesGeorgakopoulos C.
Drug Test Anal. 2020 Mar;12(3):323-330. doi: 10.1002/dta.2723.
A novel mixed living high training low intervention and the hematological module of the athlete biological passport.Voss, S. C., Al-Hamad, K., Samsam, W., Cherif, A., Georgakopoulos, C., Al-Maadheed, M., Balanos, G., Lucas, S., Sottas, P. E., Wilson, M., & Townsend, N.
2021
Front Mol Biosci. 2021 Oct 26;8:728273. doi: 10.3389/fmolb.2021.728273
Integrating Whole Blood Transcriptomic Collection Procedures into the Current Anti-Doping Testing System, Including Long-Term Storage and Re-Testing of Anti-Doping Samples.Lima, G., Kolliari-Turner, A., Malinsky, F. R., Guppy, F. M., Martin, R. P., Wang, G., Voss, S. C., Georgakopoulos, C., Borrione, P., Pigozzi, F., & Pitsiladis, Y.
Bioanalysis. 2021 Oct;13(19):1511-1527.doi: 10.4155/bio-2021-015
Olympic anti-doping laboratory: the analytical technological road from 2016 Rio De Janeiro to 2021 Tokyo. Saad, K., Salama, S., Horvatovich, P., Al-Maadheed, M., & Georgakopoulos, C.
Front Mol Biosci. 2021 Sep 1;8:723858. doi: 10.3389/fmolb.2021.723858.
Proteomic Analysis of Cardiac Adaptation to Exercise by High Resolution Mass Spectrometry.Al-Menhali, A. S., Anderson, C., Gourine, A. V., Abramov, A. Y., D'Souza, A., & Jaganjac, M. (2021).
Rapid Commun Mass Spectrom. 2021 Sep 15;35(17):e9141. doi: 10.1002/rcm.9141.
Ultra-fast retroactive processing by MetAlign of liquid chromatography/high-resolution full-scan Orbitrap mass spectrometry data in WADA Human Urine Sample Monitoring Program.Khelifi, S., Saad, K., Vonaparti, A., Mahieddine, S., Salama, S., Saleh, A., Al-Mohannadi, M., Al-Thaiban, H., Lommen, A., Horvatovich, P., Beotra, A., Abushareeda, W., Al-Maadheed, M., & Georgakopoulos, C.
Phytomedicine Plus. 2021 August 1(3), 100078.
20-Hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner.Orie, N. N., Raees, A., Aljaber, M. Y., Mohamed-Ali, N., Bensmail, H., Hamza, M. M., Al-Ansari, N., Beotra, A., Mohamed-Ali, V. and Almaadheed, M., & Al-Maadheed, M.
Drug Test Anal. 2021 Aug 28. doi: 10.1002/dta.3157
Red blood cell derived extracellular vesicles during the process of autologous blood doping.Voss, S. C., Yassin, M., Grivel, J. C., Al Hmissi, S., Allahverdi, N., Nashwan, A., Merenkov, Z., Abdulla, M., Al Malki, A., Raynaud, C., Elsaftawy, W., Al Kaabi, A., Donati, F., Botre, F., Mohamed Ali, V., Georgakopoulos, C., & Al-Maadheed, M.
Drug Test Anal. 2021 Jul;13(7):1341-1353. doi: 10.1002/dta.3032.
Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)-SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti-doping samples.Kraiem, S., Al-Jaber, M. Y., Al-Mohammed, H., Al-Menhali, A. S., Al-Thani, N., Helaleh, M., Samsam, W., Touil, S., Beotra, A., Georgakopoulas, C., Bouabdallah, S., Mohamed-Ali, V., & Al-Maadheed, M.
Drug Test Anal. 2022 May;14(5):826-832. doi: 10.1002/dta.3123
The use of RNA-based 5'-aminolevulinate synthase 2 biomarkers in dried blood spots to detect recombinant human erythropoietin microdoses.Loria, F., Cox, H. D., Voss, S. C., Rocca, A., Miller, G. D., Townsend, N., Georgakopoulos, C., Eichner, D., Kuuranne, T., & Leuenberger, N. (2021).
Viruses. 2021 Apr 28;13(5):786.
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 CohortSmith, Muneerah, Houari B. Abdesselem, Michelle Mullins, Ti-Myen Tan, Andrew J. M. Nel, Maryam A. Y. Al-Nesf, Ilham Bensmail, Nour K. Majbour, Nishant N. Vaikath, Adviti Naik, Khalid Ouararhni, Vidya Mohamed-Ali, Mohammed Al-Maadheed, Darien T. Schell, Seanantha S. Baros-Steyl, Nur D. Anuar, Nur H. Ismail, Priscilla E. Morris, Raja N. R. Mamat, Nurul S. M. Rosli, Arif Anwar, Kavithambigai Ellan, Rozainanee M. Zain, Wendy A. Burgers, Elizabeth S. Mayne, Omar M. A. El-Agnaf, and Jonathan M. Blackburn.
Drug Test Anal. 2021 Mar;13(3):529-538. doi: 10.1002/dta.2957
Horseradish-peroxidase-conjugated anti-erythropoietin antibodies for direct recombinant human erythropoietin detection: Proof of concept.Voss, S. C., Orie, N. N., El-Saftawy, W., Saghbazarian, S., Al-Kaabi, A., Georgakopoulos, C., Athanasiadou, I., Mohamed-Ali, V., & Al-Maadheed, M.
Drug Test Anal. 2021 Feb;13(2):460-465. doi: 10.1002/dta.2954
Biosafety Level 2 cabinet UV-C light exposure of sports antidoping human urine samples does not affect the stability of selected prohibited substances.Voss, S., Abushreeda, W., Vonaparti, A., Al-Wahaibi, A., Al-Sowaidi, N., Al-Mohannadi, I., Mahieddine, S., Khelifi, S., Salama, S., Saleh, A., Al-Mohannadi, M., El-Saftawy, W., Al-Hamad, K., Nofal, A., Dbes, N., Aguilera, R., Al-Maadheed, M., & Georgakopoulos, C.
2022
Future Sci OA. 2022 Jul 7;8(6):FSO805. doi: 10.2144/fsoa-2022-0006.
Downregulation of CYP17A1 by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties.Aljaber, M. Y., Orie, N. N., Raees, A., Kraiem, S., Al-Jaber, M., Samsam, W., Hamza, M. M., Abraham, D., Kneteman, N. M., Beotra, A., Mohamed-Ali, V., & Almaadheed, M
Metabolites. 2022 May 10;12(5):425. doi: 10.3390/metabo12050425.
Untargeted Metabolomics Identifies a Novel Panel of Markers for Autologous Blood Transfusion.Al-Nesf, A., Mohamed-Ali, N., Acquaah, V., Al-Jaber, M., Al-Nesf, M., Yassin, M. A., Orie, N. N., Voss, S. C., Georgakopoulos, C., Bhatt, R., Beotra, A., Mohamed-Ali, V., & Al-Maadheed, M.
Biomedical Journal of Scientific & Technical Research. 2022 44(1), pp.35212-35219.
A Reproducible Method for the Identification of Methandrostenolone Metabolites Using a Humanized Liver Rodent Model.AlJaber, M., Abushreeda, W., Raees, A., Vonaparti, A., Kraiem, S., AlSowaidi, S., Saad, K., Georgakopoulos, C., Mohamed-Ali, V., Maadheed, M.A. and Lund, G.
Int J Environ Res Public Health. 2022 Feb 17;19(4):2266.doi: 10.3390/ijerph19042266.
A Retrospective Study of Non-Communicable Diseases amongst Blue-Collar Migrant Workers in Qatar. Al-Hatimy, F., Farooq, A., Al Abiad, M., Yerramsetti, S., Al-Nesf, M. A., Manickam, C., Al-Thani, M. H., Al-Khater, A. H., Samsam, W., Mohamed-Ali, V., & Al-Maadheed, M.
Nature Communications. 2022 Feb 17;13(1):946.doi: 10.1038/s41467-022-28639-4
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications.Al-Nesf MAY, Abdesselem HB, Bensmail I, Ibrahim S, Saeed WAH, Mohammed SSI, Razok A, Alhussain H, Aly, Al Maslamani M, Ouararhni K, Khatib MY, Hssain AA, Omrani AS, Al-Kaabi S, Al Khal A, Al-Thani AA, Samsam W, Farooq A, Al-Suwaidi J, Al-Maadheed M, Al-Siddiqi HH, Butler AE, Decock JV, Mohamed-Ali V, Al-Ejeh F.
bioRxiv. 2022 Feb 02.09.479669.
Auto-Immunoproteomics Analysis of COVID-19 ICU Patients Revealed Increased Levels of Autoantibodies Related to Male Reproductive System.Frank Schmidt, Houari B. Abdesselem, Karsten Suhre, Muhammad U. Sohail, Maryam Al-Nesf, Ilham Bensmail, Fathima Mashod, Hina Sarwath, Joerg Bernhardt, Ti-Myen Tan, Priscilla E Morris, Edward J. Schenck, David Price, Nishant N. Vaikath, Vidya Mohamed-Ali, Mohammed Al-Maadheed, Abdelilah Arredouani, Julie Decock, Jonathan M. Blackburn, Augustine M.K. Choi, Omar M. El-Agnaf.